Chinese scientists reveal human developmental cell maps of the digestive tract

How many kinds of cell types do humans have in the digestive tract and what do they “long”? After many years of joint research, Chinese scientists have for the first time in the world fully and systematically clarified the four organs of the esophagus, stomach, small intestine, and large intestine during the development of human embryos. The gene expression maps and their signal regulation mechanisms provide comprehensive and informative developmental cell map data for the field of gastrointestinal biology research.

The research results obtained by the joint research teams of the Beijing Institute for Advanced Genetics Advanced Genetics (ICG), Peking University Biodynamic Imaging Center, and the Third Hospital of Peking University have recently been published in the internationally renowned academic journal Natural Cell Biology. Published online.

The digestive tract is the most important component of the human digestive system, consisting mainly of the esophagus, stomach, small intestine, and large intestine. It reveals the gene expression regulatory networks and “cell type maps” of these four organs during human embryonic development and is a developmental organism. One of the major issues in the field of study.

“This research is the first time in the world to fully and systematically reveal the precise developmental pathways and gene expression characteristics of different cell types of the four organs under single cell resolution and whole transcriptome conditions.” Professor Shengfu Fu, deputy director of the Advanced Genetic Diagnosis Center for Advanced Genetic Diagnosis in Beijing, is studying single-cell functional genomics for embryonic and germline development. (According to Xinhua News Agency)


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