The world's first bio-corneal "Ai Xinyi" second generation was approved for listing
"If I can see it, life may be completely different... is it that God has covered the curtain in front of my eyes and forgot to open it."
In 2002, Xiao Huangqi, a singer who was blinded by congenital cataract, launched the song "You are my Eye", and even deep personal feelings have revealed the dilemma caused by visual impairment. In May 2015, the world's first bioengineered cornea “Ai Xinyiâ€, which was independently researched and developed by researchers of China Regenerative Medicine Group, was approved for the market, bringing light and hope to patients with visual impairment who are waiting in the dark night.
Recently, the reporter walked into Shenzhen Ai Niang Corneal Engineering Co., Ltd. (hereinafter referred to as “Ai Nierâ€), a subsidiary of China Regenerative Medicine Group located in Zhonghaixin Innovation Industrial City, Longgang District, to explore the porcine cornea--"Ai Xinyi "The story behind R&D and production.
Launched the second generation product full-layer cornea development
When Ai Xinyi appeared, it caused a sensation in the medical profession. The reporter learned from Ai Nier that the company has launched the research and development of the second-generation product "full-layer cornea". In the near future, this Longgang local company will once again be amazing in the world.
"We are working with the Shandong Institute of Ophthalmology, led by Xie Lixin, the only academician in China's ophthalmology industry, to develop a second-generation product that takes about four to five years and will be available in the fastest 2021." Vice President, China Regenerative Medicine Group, Zhang Ai, general manager of Ai Nier, said.
Ai Xinyi's second-generation product development team consists of five elite researchers. Each member has a strong background in research, one of whom returned from studying in Sweden and one returned from studying in the UK. The reporter learned from the R&D team that the research and development of the second generation products is progressing smoothly.
Unlike the first generation, the second generation contains an active layer of endothelial cells. According to Zhang Aibing, the human cornea has the characteristics of thin middle and thick sides, and its normal thickness is about 600 microns. The human cornea is divided into 5 layers, and the outermost non-keratinized squamous epithelium with a thickness of about 50 microns is called the corneal epithelium. Corneal epithelium and stromal layer are often damaged by disease or trauma, which can lead to blindness. It can be treated with laminectomy by Aisin. "If the endothelial layer of the patient's cornea is damaged, it can only be replaced by a fresh donor cornea, and this cornea is seriously lacking. The second generation of Ai Xinyi is expected to solve this problem."
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