Test-tube baby carrying three genes is expected to be born two years later

Release date: 2014-06-06

IVF technology with three genes involves genetic changes that raise moral concerns

If nothing else, scientists will be able to "create" IVFs carrying three genes in about two years. This "three-person IVF" technology will be used to avoid genetic diseases caused by defects in the mitochondrial DNA. Unlike conventional IVF, it requires two female-supplied eggs and one male-supplied sperm.

British regulators say there is no evidence that the technology is not safe, but more tests are needed. One out of every 6,500 newborns in the UK has a disease caused by severe mitochondrial gene defects. The main symptoms include lack of energy, muscle weakness, blindness, heart problems, and even death. The disease is passed on from the mother to the baby.

The assessment report of the “three-person IVF” technology by the supervisory authority and the expert evaluation team believes that due to careful consideration, the last few tests need to be completed to give the technology a green light. These final tests are expected to take two years.

Because the "three-person IVF" technology involves transforming human genes, it has caused moral concern; activists worry that it will become the forerunner of the birth of genetically modified people.

The British government is also required to formulate or amend relevant legislative provisions. The “three-person IVF” technical assessment commissioned by the UK Ministry of Health is part of a large-scale public consultation exercise initiated by the government. The Ministry of Health will publish public consultation results in the coming months and give a timetable for regulatory changes and mechanism adjustments. The basic attitude of the government is that the development of this technology will make the UK a pioneer in this field, and the scientific community hopes that the government will accelerate its regulatory adjustments.

Source: Bio 360

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