Harvard scientists have developed a "new weapon" to capture cancer cells, and the cancer war is winning!
Release date: 2017-06-30
Malignant tumors are powerful enemies that cause blood vessels to help their greedy growth, damage neighboring tissues, and deploy many strategies to escape the body's defense system. Even worse, the release of circulating tumor cells (CTCs), which secretly move in the blood and flow to other parts of the body, is the transfer of cancer. CTCs are dangerous, but their presence is also a valuable indicator of a patient's disease stage. Unfortunately, finding a relatively small number of CTCs in trillions of healthy cells is like finding a needle in a haystack.
To solve this problem, researchers at the WYSS Institute at Harvard University have developed a protein that modifies human blood opsonin, called FcMBL, which was originally used as a broad-spectrum pathogen capture agent to target CTCs. Using FcMBL-coated magnetic beads, the researchers were able to successfully capture 90% of seven different types of cancer cells.
The researchers said: "We are able to quickly isolate CTC from the blood. This new technology is very useful for the diagnosis of cancer. It is a very advanced biological system. This study heralds the birth of a new weapon for cancer war. In the second trial, the researchers implanted fluorescent markers in breast cancer mice, and after the tumor developed for 28 days, blood tests were used to determine the number of CTCs, then they mixed the blood FcMBL-encapsulated beads and allowed the beads to float in the magnet. By measuring the speed of movement of normal cells and cancer cells, our magnetic beads are attached to fast-moving cancer cells. Then we tested other types of cancer, including non-small cell lung cancer, glioblastoma, etc. The same applies, and it is believed that through further argumentation, our new weapon may become a new tool for detecting cancer in the future."
Source: Noble
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