Biomaterials: Micro-needle vaccination technology is coming, the flu is going away
Release date: 2015-07-20
Scientists from Osaka University have recently used the micro-acupuncture that can dissolve in the skin to transport influenza vaccines, which successfully protects the injectors from the flu infection. This new injection method is more standard than the standard vaccine injection. Efficient and convenient, related research published in the international magazine Biomaterials .
According to the researchers, the solubilized microneedles make vaccination safer, more convenient, and less painful. According to World Health Organization data, immunization can effectively suppress about 2 million to 3 million deaths per year, while H1N1 swine flu and Other infectious diseases such as the widespread epidemic of Ebola virus may pose significant challenges for vaccine development and vaccination. Most vaccines are injected through the skin or muscles, and new vaccination techniques may improve vaccines. Unnecessary risks and diseases caused by syringe injection.
This soluble microneedle patch is made from a dissolvable material that eliminates the risk of acupuncture injections and does not require personal medical training. This new type of microneedle gives some development The areas where China’s health resources are scarce are of great help. Researcher Professor Shinsaku Nakagawa said that this new injection method uses a soluble micro-needle patch as a vaccine delivery system, which will be widely used. Because this micro-needle patch is very easy to use, we It is believed to be effective in helping vaccination efforts for the population of developing countries. The researchers named the new microneedle patch MicroHyala, which dissolves in water. The small needle-like structure consists of hyaluronic acid. When the patch is used like cement, the microneedle pierces the top of the skin. In the body, it also releases the vaccine it carries.
In this study, the researchers compared the efficacy of this new injection technique with conventional vaccination techniques against individuals with three influenza viruses: A/H1N1, A/H3N2 and B. It has been shown that such microneedle patches can inoculate individuals more effectively, while also allowing the vaccinated individual to produce an equivalent or stronger immune response. In the previous study, the researchers evaluated the efficacy of micro-needle made of silicon and metal, but the results were not satisfactory. In this paper, the micro-needle structure made of soluble material can effectively inject the vaccine, and at the same time Eliminating the risks caused by conventional injections, the researchers hope to promote the vaccination method of this micro-needle patch later, and this new injection method will also help to improve the health of the body.
Source: Bio Valley
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