Scientists prove that brain stimulation can improve symptoms of diabetes
Release date: 2018-05-28
The brain is becoming an important regulator of systemic glucose metabolism. Data accumulated from animal and observational human studies suggest that striatal dopamine signaling plays a role in glucose regulation, but there has been a lack of direct evidence. Recently, an evidence from Yale University in the Netherlands and the United States indicates that deep brain stimulation (DBS) can help treat type 2 diabetes.
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Related research was published in the journal Science Translational Medicine on May 23 under the title "Striatal dopamine regulates systemic glucose metabolism in humans and mice". In this paper, the research team described what happened to a person with a mental disorder who underwent DBS treatment.
DOI: 10.1126/scitranslmed.aar3752
According to the researchers, the story begins with an OCD patient who does not respond to traditional therapies, and his doctor suggests trying DBS (previously DBS therapy has been shown to work for other patients with the same condition). After treatment, the doctor found that the patient not only improved the symptoms of OCD (obsessive-compulsive disorder), but also the symptoms of type 2 diabetes. This led them to further test other obsessive-compulsive patients who received DBS treatment. By doing so, they found that all subjects had an increased sensitivity to insulin.
The researchers explained that during the DBS process of obsessive-compulsive disorder, a small amount of current is concentrated in the part of the brain called the nucleus accumbens (it has been found to be responsible for motivation and reward processing to some extent). ), a slight vibration helps to restore the line to normal. But in this study, new findings demonstrate that DBS also stimulates the ventral striatum involved in regulating glucose levels in the body.
The causes of type 2 diabetes include poor diet, lack of exercise, and a combination of susceptibility genes. These factors can destroy the body's ability to produce insulin, which in turn leads to elevated levels of glucose in the blood, causing more problems. Current treatments for diabetic patients typically involve the injection of insulin or a drug that causes the liver to produce less glucose and/or make the cells more sensitive to insulin. It now appears that DBS can do much the same thing, that is, make cells more sensitive to insulin.
Finally, it is important to emphasize that researchers do not recommend DBS as a treatment for diabetes because it is too invasive. But they believe that this finding may help develop other similar treatments.
Reference materials:
Deep brain stimulation found to improve diabetes symptoms
Source: Bio-Exploration
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