Japanese researchers discover new treatments for leukemia
Release date: 2018-03-05
Japanese researchers have found in the experiment that a gene plays a role in preventing immunity in experimental mice. If this gene is removed, the mouse with leukemia will be cured. This discovery will help develop new drugs for the treatment of leukemia.
A research team at the Graduate School of Medicine of Kyoto University found that a gene called "Sipa1" plays a role in preventing immunity in experimental mice. After the researchers removed the gene from the experimental mice, the rats were transplanted with chronic myeloid leukemia cells. As a result, 100 diseased mice were cured within 15 days, while the rats without the gene were excluded in the comparison experiment. All died of leukemia.
This experiment shows that the immune cells of the experimental mice that have eliminated this gene can play a role in defeating leukemia. However, the mice that knocked out this gene were more susceptible to other diseases, although the leukemia was cured.
Researchers believe the findings will help develop new leukemia treatments. They will study how to eliminate this gene, but use drugs to control the role of this gene, so that immune cells function. The results of this research have been published in the British journal Nature Communications.
Source: Xinhuanet
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