Germany designed peptide molecules that seal blood vessels

Release date: 2009-06-02

Researchers at the University of Würzburg, Germany, have designed a peptide molecule that seals the bleeding blood vessels. There is a layer of adhesion protein on the surface of human blood vessels that protects blood vessels, but in many cases, the condition of this layer of proteins is unstable, such as sepsis. When the virus invades the blood vessels, it will spread in the human body. The blood with the virus will penetrate outside the blood vessels, causing other organs and body tissues to swell.
Experts used a computer to design a small peptide molecule that enhances the stability of vascular adhesion proteins and seals the site of vascular bleeding. Professor Detrof Drenkoha of the University of Würzburg, Germany, said that the action of small peptide molecules is like glue between two cements. This result will take a long time in clinical application, but for the treatment of vascular bleeding. The disease has opened up a new avenue. Professor Drenkeha said that it is difficult for the body to naturally secrete this peptide molecule. Because the human body does not have this function, the next step researchers will look for substances similar to the chemical structure and efficacy of this peptide molecule.
There is currently no effective way to seal blood vessels in medicine, which is also very much needed in many operations. Shanghai Medical Device Industry Association

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