China should accelerate the research of biomedical applications of terahertz technology

Many patients need to do a series of examinations such as X-ray, CT, and MRI when they are in the hospital. Terahertz (THz) waves, an electromagnetic band that has not been fully developed, may change this.

Recently, at the 488th Xiangshan Science Conference on the theme of "Terhus Wave in Scientific Issues and Frontier Technologies in Biomedical Applications", experts at the conference pointed out that terahertz waves have fingerprint characteristics of the structure and properties of reactive substances, and The photon energy is low, far less than the X-ray energy, and does not cause harmful ionization to biological macromolecules, biological cells and tissues, and is particularly suitable for biopsy of biological tissues. Therefore, compared to existing medical imaging technologies, terahertz wave spectral imaging technology has more unique and more suitable physical characteristics.

The terahertz wave is an electromagnetic wave with a frequency of 0.1-10 THz, which is in the transition band from macroscopic electronics to micro-visualization. Internationally, terahertz biomedical research was officially launched with the international joint project "THz-Bridge" established by the European Union in 2000. The US government has named terahertz technology as one of the "Top Ten Technologies for Changing the Future of the World". Japan has listed it as the "Top Ten Strategic Targets of the National Pillar" and listed biomedical applications as one of the main directions. Europe Biomedical applications have also been the primary research direction for 10 consecutive years.

Academician Yao Jianwei, one of the executive chairmen of the conference, said that many large-scale international cooperation projects have been carried out around the terahertz technology biomedical application research. At present, some representative achievements have been made in the biological monitoring and biological effects research of terahertz technology biomacromolecules, cells, tissues and organs at home and abroad.

Academician Du Xiangyu, one of the executive chairmen of this meeting, pointed out that among all physical technologies, electromagnetic wave technology is particularly prominent in promoting medicine. Since the 1st Nobel Prize in Physics was awarded on the X-ray in 1901, five biomedical-related Nobel Prizes have been awarded to the field of X-spectrum technology. “This conference is to explore the intersection of terahertz technology and biomedical frontiers and promote in-depth research and cooperation in this field.”

In response to the application of terahertz technology in biomedicine, Professor Cui Hongliang of Jilin University introduced that biomacromolecule interaction is a key cause of major life phenomena and lesions, while terahertz photon energy covers the energy level range of biomacromolecular spatial conformation. . This band contains important information such as the spatial conformation that cannot be detected by other electromagnetic bands and directly represents the function of biological macromolecules. Therefore, it is possible to develop a new theory and technology that utilizes terahertz detection and intervention in the process of biological macromolecule interaction, and provides advanced technical means for the diagnosis and effective intervention of major diseases.

The terahertz technology is finally applied to the field of biomedicine, and it needs to be implemented on specific medical equipment to form a certain scale in industrialization.

"The core technology and clinical equipment of China's laboratory medicine are mainly monopolized by foreign countries, and the market share of domestic brands is extremely low." Professor Wei Ling of the Southwest Hospital of the Third Military Medical University is worried about this. He pointed out: "At present, the detection theory and key technologies of terahertz wave detection molecules and cells are the first research in China that is carried out simultaneously with the world, and will provide a revolutionary science for molecular and cellular detection in the field of laboratory medicine from a new perspective. Means, it is expected to clarify and provide a new theory and technical system of laboratory medicine, forming a new discipline and industrial base for terahertz wave-testing medical advantages."

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