Antidepressant 99% Venlafaxine Hydrochloride CAS 99300-78-4 for Antidepressant Drug

Antidepressant 99% Venlafaxine Hydrochloride CAS 99300-78-4 for Antidepressant Drug

 


Description:

Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class.This means it increases the concentrations of the neurotransmitters serotonin and norepinephrine in the body and the brain.

A comparative meta-analysis of 12 major antidepressants found that venlafaxine, mirtazapine, escitalopram, and sertraline were significantly more efficacious than duloxetine, fluoxetine, fluvoxamine, paroxetine, and reboxetine.A combination of venlafaxine and mirtazapine achieved remission rates (defined as a HAM-D score of 7 or less) of 58% in one controlled trial.In combination with an antipsychotic medicine aripiprazole, better results in treatment resistant depression in older adults have been demonstrated.

Venlafaxine is used primarily for the treatment of depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms.At low doses (<150 mg/day), it acts only on serotonergic transmission. At moderate doses (>150 mg/day), it acts on serotonergic and noradrenergic systems, whereas at high doses (>300 mg/day), it also affects dopaminergic neurotransmission.

Due to its action on both the serotoninergic and adrenergic systems, venlafaxine is also used as a treatment to reduce episodes of cataplexy, a form of muscle weakness, in patients with the sleep disorder narcolepsy.Some open-label and three double-blind studies have suggested the efficacy of venlafaxine in the treatment of attention deficit-hyperactivity disorder (ADHD).Clinical trials have found possible efficacy in those with post-traumatic stress disorder (PTSD).
 

Medical Use:

Venlafaxine is used primarily for the treatment of depression, general anxiety disorder, social phobia, panic disorder and vasomotor symptoms
 
 
Venlafaxine hydrochloride is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity
 

COA:
 
 
Antidepressant Related material:
 
Paroxetine
Sertraline
Fluvoxamine maleate,
Citalopram hydrobromide,
Duloxetine hydrochloride,
Venlafaxine hydrochloride
Duloxetine
Bupropion
Trazodone
Nefazodone
Mirtazapine
Moclobemide
Escitalopram
Gabapentin hydrochloride






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